A defective operating system is never a good thing. Like computers, our cells depend on operating systems to drive normal functions. Gene expression programs comprise the software code our cells rely on, with each cell type controlled by its own program. Corrupted programs can trigger disease…
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A photograph of a polar bear in captivity, no matter how sharp the resolution, can never reveal as much about behavior as footage of that polar bear in its natural habitat. The behavior of cells and molecules can prove even more elusive…
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Preparations are underway at the European Medicines Agency together with European Member States and the European Commission, for the introduction of the new pharmacovigilance legislation in July this year. The new legislation will represent the biggest change to the legal framework since The Agency was founded in 1995…
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Major blockbuster drugs are facing the end of their era and big pharma companies are bracing for the effect in hopes that they will find a solution for their dwindling pipelines. Thus new opportunities and challenges are rising in the practice of open innovation and Fleming Europe will be there to explore them…
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NextLevel Pharma’s “Advancing clinical research in Turkey, the Middle East and North Africa” conference will bring together the local regulators and ethics committees, alongside experienced investigators and study personnel, as well as clinical trial experts from pharma and CROs…
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Cells rely on purines, which are types of molecules that make up half of the DNA and RNA building blocks, and are a key component of the chemicals that store a cell’s energy in order to perform many vital functions. The purine supply is strictly controlled by the cells, with any disruption likely to cause serious potential consequences…
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Bypassing the stem cell stage, researchers at the Stanford University School of Medicine in California converted mouse skin cells directly into neural precursor cells, the cells that go on to form the three main types of cell in the brain and nervous system. They write about their findings in the 30 January early online issue of the Proceedings of the National Academy of Sciences…
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Asian markets are increasingly the focus of pharmaceutical companies who are looking for new market opportunities beyond the traditional “rich-world” countries who are facing economic stagnation…
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Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions…
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Like a magician employing sleight of hand, the protein mitoNEET - a mysterious but important player in diabetes, cancer and aging - draws the eye with a flurry of movement in one location while the subtle, more crucial action takes place somewhere else…
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