(BUSINESS WIRE)–Bristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co., Ltd. announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for ABILIFY® (aripiprazole) for the treatment of irritability associated with autistic disorder in pediatric patients ages 6 to 17 years, including symptoms of aggression towards others, deliberate self-injuriousness, temper tantrums, and quickly changing moods.
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Effient(R) (prasugrel) tablets, a new antiplatelet medicine, was added as a treatment option in two clinical guideline updates: one for patients receiving percutaneous coronary intervention (PCI) and a second one for patients with ST elevation myocardial infarction (STEMI), or severe heart attack.
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Search the Internet to learn about your asthma, high cholesterol or other common disorder, and odds are you’ll be directed to a pharmaceutical company-sponsored Web homepage. There you’ll often find an offer for a free sample or a one-time discount on a top-selling prescription medication. Is it a good deal? Not according to a study of such direct-to-consumer offers on the Internet by a research team led by Dr. William G.
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A novel approach to classify the gender of six-week-old turkey poults could save millions of male chicks from being killed shortly after birth, according to Dr. Gerald Steiner from the Dresden University of Technology in Germany and his team. Their use of infrared spectroscopy to determine the gender of young birds shows that it is a fast and accurate method with the potential to be used by the breeding industry to identify and select female eggs for breeding.
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Whitehead researchers have developed a new type of genetic screen for human cells to pinpoint specific genes and proteins used by pathogens, according to their paper in Science. In most human cell cultures genes are present in two copies: one inherited from the father and one from the mother. Gene inactivation by mutation is therefore inefficient because when one copy is inactivated, the second copy usually remains active and takes over.
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If you’re like most people, you probably think chemistry is too difficult to bother with outside of school and too clinical to be any fun. But chemistry offers a magic and elegance to behold: from the fascination of fall foliage and fireworks to the fundamentals of digestion (as when good pizza goes bad!) there is a true ‘joy’ in chemistry. Cathy Cobb and Monty L.
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It seems obvious that naturally waking up from sleep and being startled by something in the environment are two very different emotional states. However, the neuroscience that underlies these different forms of arousal has, for the most part, remained a mystery. Now, new research published by Cell Press in the November 25 issue of the journal Neuron demonstrates that there are at least two completely separate and independent forms of arousal in fruit flies.
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You wouldn’t want a car with no brakes. It turns out that the developing brain needs them, too. Researchers at the Stanford University School of Medicine have identified a set of molecular brakes that stabilize the developing brain’s circuitry. Moreover, experimentally removing those brakes in mice enhanced the animals’ performance in a test of visual learning, suggesting a long-term path to therapeutic application. In a study to be published Nov.
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Over the course of a lifetime, the heart pumps some 250 million liters of blood through the body. In order to do this, the muscle fibers of the heart have to be extremely durable. The research group headed by Dr. Wolfgang Rottbauer, vice chair of the Department of Medicine III at Heidelberg University Hospital (Chairman: Prof. Dr. H. A. Katus), has discovered a protein that is responsible for the stability of the smallest muscular unit, the sarcomere.
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The so-called RANK protein and the molecule that binds to it, the RANK ligand or RANKL, form a focus of the work of Josef Penninger, director of the Institute of Molecular Biotechnology (IMBA) in Vienna. In 1999 his group deleted the RANKL gene from mice and showed that the RANK/RANKL system was the “master regulator” governing bone loss (Kong et al. 1999 Nature 402, 304-309).
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