Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research.
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Registration is underway for the 10th International Conference on Systems Biology (ICSB). The conference will be held at Stanford University from August 30th - September 4th. “This is the first time the International Conference on Systems Biology has come to the San Francisco Bay Area.
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John Spence, a physicist at Arizona State University, is a longtime user of the Advanced Light Source at Lawrence Berkeley National Laboratory, where he has contributed to major advances in lensless imaging. It’s a particularly apt propensity for someone who works with x-rays, since they can’t be focused with ordinary lenses. As new light sources evolve to produce brighter x-rays in faster pulses, lensless imaging becomes ever more critical for science.
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An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being funded in part by a $1.
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In cancer research, as in most other biomedical sciences, they are playing a key role: living cells, kept in sterile plastic containers with red culture media populating incubators in laboratories around the world. But do researchers always know what is really living in their culture dishes? Under the microscope, different cell lines are almost impossible to distinguish from each other.
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Pharmaceutical companies, hospitals, advocacy groups and others with a stake in health reform continue to lobby in hopes of winning concessions in the overhaul, or at least surviving the changes unscathed. “One of the groups key to working any deal is the pharmaceutical industry, which has been quite active behind the scenes,” National Public Radio reports.
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“The healthcare overhaul fight in Washington is bursting into America’s living rooms, and interests from many bands on the political spectrum are trying to transform an often wonky debate over 1,000-page bills into an emotional pitch that can be captured in 30 seconds,” The Boston Globe reports.
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AstraZeneca (NYSE: AZN) announced the company has submitted a New Drug Application to the U.S. Food and Drug Administration (FDA) and a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMEA) for an investigational drug, vandetanib 100 mg for use in combination with chemotherapy for the treatment of advanced non-small cell lung cancer in patients previously treated with one prior anti-cancer therapy. The U.S.
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United Therapeutics Corporation (Nasdaq: UTHR) announced that the United States Food and Drug Administration (FDA) has approved TYVASO (treprostinil) Inhalation Solution for the treatment of pulmonary arterial hypertension (PAH) using the TYVASO Inhalation System (which includes the Optineb-ir device and accessories).
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Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) announced finalization of the protocol for the Company’s Phase II trial of ANA598 in combination with pegylated interferon-alpha and ribavirin in hepatitis C patients. Allowance of the protocol has been received from the United States Food and Drug Administration (FDA), and patient dosing is expected to commence within the next several weeks.
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