Scientists have uncovered an interesting connection between two important protein kinase signaling pathways that are associated with cancer. The research, published by Cell Press in the January 30th issue of the journal Molecular Cell, may direct new therapeutic strategies for multiple types of cancer. The protein kinase LKB1 is a known tumor suppressor and the LKB1-AMPK signaling pathway couples energy metabolism with cell growth, proliferation and survival.
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Novartis and Medicines for Malaria Venture (MMV) announced the launch of Coartem® Dispersible, a new pediatric formulation of Coartem® (artemether/lumefantrine 20 mg/120 mg), for the treatment of uncomplicated malaria in infants and children.
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In a new study, Cymbalta (duloxetine HCl) 60-120 mg, taken once daily, reduced pain severity significantly, compared with placebo, in patients with osteoarthritis pain of the knee. Data from the 13-week randomized, double-blind, placebo-controlled clinical trial(1) were presented at the annual meeting of the American Academy of Pain Medicine (AAPM) in Honolulu, Hawaii.
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Laird Christianson Advertising laid off seven employees this week.

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San Francisco State University, UC Berkeley, UCSF, Stanford University, the J. David Gladstone Institutes and San Jose State University are among 26 institutions that will share in a $58 million training program to aid stem cell research from the California Institute for Regenerative Medicine.

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Three executives of Bioject Medical Technologies Inc. have agreed to reduce their salaries by 20 percent, beginning Feb. 1.

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A.M. Best Co. has placed the financial strength and issuer credit ratings of Capital District Physicians’ Health Plan, Inc. and subsidiary CDPHP Universal Benefits Inc. (UBI) under review with negative implications.

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FNB United Corp. reports a fourth-quarter net loss of $3.9 million, or 34 cents per diluted share. In the same period last year, the company earned $1.3 million, or 11 per diluted share. (FNBN)

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Roche Holding AG took its bid for Genentech Inc. directly to shareholders Friday, offering about $42.1 billion, about $1.6 billion lower than its previous offer. (DNA)

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Frost Insurance has agreed to offer liability insurance to members of the Texas Association of Business who serve as directors and officers of for-profit and non-profit organizations, including chambers of commerce. (CFR)

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